Sample pretreatment method for virus detection
OwnerHong Jai Leeinventor
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Abstract
The present invention relates to a method for detecting a virus, and more particularly, to a method for detecting a virus including a lipid bilayer envelope, wherein the method allows a surface antigen, which is a lipid bilayer envelope protein, to be effectively exposed from lipoproteins that mask all or part of the envelope protein, thereby revealing the surface antigen that is masked by the lipoproteins, so that a probe such as an antibody can be used to detect the virus with high sensitivity within a short time.
Claims13
A method for pretreating a biological sample for virus detection, the method comprising:
- (1) isolating an enveloped virus including a lipid bilayer envelop from the biological sample;
- and
- (2) treating the enveloped virus with a bile acid, a bile acid derivative, and/or a pH adjusting agent.
A composition for pretreating a biological sample for enveloped virus detection, the composition comprising a bile acid, a bile acid derivative, and/or a pH adjusting agent as an active ingredient(s).
Dependencies are inferred from the claim text.