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AssigneeOxford University Innovation Limited
InventorsRegent LEE, Mohammad ALKHALIL, Giovanni Luigi DE MARIA, Claire VALLANCE, Keith CHANNON
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A method of characterizing a sample comprising a thrombus collected from a patient is described. The method comprises illuminating the sample with electromagnetic light, detecting light reflected or Raman scattered by the sample at a plurality of wavelengths, and classifying the sample based on a spectral analysis of the detected reflected or Raman scattered light. The spectral analysis may comprise principal component analysis PCA, discriminant function analysis DFA, or cluster analysis. The classification may be according to thrombus color, i.e., erythrocyte rich “red” versus erythrocyte poor “white”, or according to degree of a clinical marker, e.g., microvascular obstruction MVO.
A method of characterising a sample comprising thrombus collected from a patient, the method comprising:
A method according to 6, wherein the step of classifying the composition of the sample using the reflectances comprises
A method of characterising a sample comprising thrombus collected from a patient, the method comprising classifying the composition of the sample using a spectral analysis of detected electromagnetic radiation scattered at a plural number of wavelengths by the sample that is illuminated with optical electromagnetic radiation.
An apparatus for characterising a sample comprising thrombus collected from a patient, the apparatus comprising an optical measurement device arranged to receive the sample and comprising an illumination system arranged to illuminate the sample with optical electromagnetic radiation and a detector arranged to detect electromagnetic radiation scattered by the sample at a plural number of wavelengths.
Dependencies are inferred from the claim text.