Detection of mutations regarding one or more deoxyribonucleic acid sequences using deterministic lateral displacement arrays

A method, comprising:

• supplying a target molecular probe and a sample of genetic material to a nanoscale deterministic lateral displacement array, the target molecular probe having an affinity to bond to a target nucleic acid sequence, and the sample of genetic material having a hybridized reference molecular probe;
• determining an amount of the target molecular probe that exits the nanoscale deterministic lateral displacement array via a bumped flow path;
• determining an amount of the hybridized reference molecular probe that exits the nanoscale deterministic lateral displacement array via the bumped flow path;
• and
• determining whether the sample of genetic material has a mutation based on a ratio of the amount of the target molecular probe that exits the nanoscale deterministic lateral displacement array via the bumped flow path to the amount of the hybridized reference molecular probe that exits the nanoscale deterministic lateral displacement array via the bumped flow path.