Technique for controlling molecular weight of pha copolymer produced by halobacterium

A method for producing polyhydroxyalkanoic acid having a weight average molecular weight of at least about 1 million g/mol, comprising culturing a microorganism to obtain the polyhydroxyalkanoic acid as a culture product,

• wherein the culture comprises a carbon source comprising a sugar,
• wherein the sugar is selected from the group consisting of:
• (a) glucose and/or a derivative thereof;
• (b) glucose and/or a derivative thereof as well as one or more of xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose, and derivatives thereof;
• and
• (c) one or more of xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose, and derivatives thereof.

A method of culturing a microorganism and controlling the weight average molecular weight of polyhydroxyalkonic acid obtained as a culture product,

• wherein the culture comprises a carbon source comprising a sugar,
• wherein the sugar is selected from the group consisting of:
• (a) glucose and/or a derivative thereof;
• (b) glucose and/or a derivative thereof as well as one or more of xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose, and derivatives thereof;
• and
• (c) one or more of xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose, and derivatives thereof,
• wherein the weight average molecular weight of the polyhydroxyalkanoic acid is between 1 million and 6 million g/mol.

A method for producing polyhydroxyalkanoic acid comprising culturing a microorganism to obtain polyhydroxyalkanoic acid as a culture product,

• wherein the culture comprises a carbon source comprising a sugar and a furfural compound,
• wherein the sugar is selected from the group consisting of:
• (a) glucose and/or a derivative thereof;
• (b) glucose and/or a derivative thereof as well as one or more of xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose, and derivatives thereof;
• and
• (c) one or more of xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose, and derivatives thereof.

A method of culturing a microorganism and controlling a molecular weight of polyhydroxyalkanoic acid obtained as a culture product,

• wherein the culture comprises a carbon source comprising a sugar and a furfural compound,
• wherein the sugar is selected from the group consisting of:
• (a) glucose and/or its derivatives;
• (b) one or more of glucose and its derivatives and xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose and/or derivatives thereof;
• and
• (c) one of more of xylose, cellobiose, glucuronic acid, arabinose, mannose, galactose, sucrose and/or derivatives thereof.