Methods of making platelets comprising modified receptors and uses thereof

Abstract

Disclosed herein are methods of producing platelets comprising a modified receptor, therapeutic agents, peptides, and/or bioactive molecules. The cells produced by the methods disclosed herein can be used to treat, manage, prevent and diagnosis, for example, lysosomal storage diseases, diabetes and cancer. The cells produced by the methods disclosed herein can be engineered to comprise receptors capable of activating platelets to trigger the release of enzymes, biomolecules or therapeutic agents upon binding to specific drugs and/or binding to tissue specific peptides.

Dependencies are inferred from the claim text.