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US 2022/0033770 A1Published application
Macs-based purification of stem cell-derived retinal pigment epithelium
AssigneeFUJIFILM Cellular Dynamics, Inc.
InventorsNathan MEYER, Lucas CHASE, Casey STANKEWICZ
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Abstract
Provided herein are methods of enriching a retinal pigment epithelium (RPE) cell population derived from stem cells. Such a method may comprise removing contaminating cells through the depletion of CD24 positive cells, CD56 positive cells, and/or CD90 positive cells from a starting population of RPE cells.
Claims18
A method for providing an enriched population of retinal pigment epithelial (RPE) cells comprising:
- a) obtaining a starting cell population comprising RPE cells;
- and
- b) enriching said starting cell population for RPE cells by removing therefrom cells that are positive for CD24, cells that are positive for CD56 and/or cells that are positive for CD90, thereby providing a RPE-enriched cell population that is enriched for RPE cells as compared to the starting cell population.
Dependencies are inferred from the claim text.