Cancer-stem-cell-specific antibody
AssigneeSapporo Medical University
InventorsTomohide Tsukahara, Toshihiko Torigoe
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Abstract
The present invention pertains to: an antibody that specifically recognizes cancer stem cells; a pharmaceutical composition containing the antibody, in particular a pharmaceutical composition for treating cancer; the utilization of these; a method for treating cancer, the method targeting cancer stem cells; etc. The above problem was solved by providing an antibody that recognizes a complex of a cancer stem cell antigen peptide and an MHC, and a pharmaceutical composition containing the antibody as an active component.
Claims13
A multispecific antibody having an antigen-binding site that recognizes a complex of an antigenic peptide derived from a protein selected from a group consisting of DNAJB8 protein, BORIS sf6 and FAM83B protein and an MHC molecule.
A pharmaceutical composition comprising an antibody that recognizes a complex of an antigenic peptide derived from a protein selected from a group consisting of DNAJB8 protein, BORIS sf6 protein and FAM83B protein and an MHC molecule.
Dependencies are inferred from the claim text.