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US 2022/0033401 A1Published application
Ampk activators
AssigneeKallyope, Inc.
InventorsIyassu SEBHAT, Shuwen HE, Ann WEBER, Nancy THORNBERRY, Lisa KRUG, Paul RICHARDS, Brett LAURING
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AssigneeKallyope, Inc.
InventorsIyassu SEBHAT, Shuwen HE, Ann WEBER, Nancy THORNBERRY, Lisa KRUG, Paul RICHARDS, Brett LAURING
Estimating the term…
This disclosure is directed, at least in part, to AMPK activators useful for the treatment of conditions or disorders associated with AMPK. In some embodiments, the condition or disorder is associated with the gut-brain axis. In some embodiments, condition or disorder is associated with systemic infection and inflammation from having a leaky gut barrier. In some embodiments, the AMPK activators are gut-restricted compounds. In some embodiments, the AMPK activators are agonists or partial agonists.
A compound of Formula (III):
Dependencies are inferred from the claim text.