Device for solid phase extraction and method for use thereof
AssigneeWaters Technologies Corporation
InventorsPamela C. Iraneta, Xin Zhang, Frank John Marszalkowski, JR.
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Abstract
Disclosed is a device for a solid phase extraction comprising two or more of the sorbents to remove phospholipids and salts from a sample, to thereby eliminate matrix effects during mass spectrometry analysis. In particular, the sorbents includes at least one sorbent which is water-wettable and contains at least one hydrophobic component and at least one hydrophilic component and at least one of sorbent having a specific affinity for a matrix interference like phospholipids. Further disclosed is a method using the device of the present invention.
Claims23
1-73. (canceled)
A solid phase extraction method, comprising:
- using a device, wherein the device comprises a sorbent bed including a sorbent containing at least one hydrophobic component and at least one hydrophilic component and a sorbent having a specific affinity to phospholipids.
The method of claim 75, wherein the sorbent that contains at least one hydrophobic component and at least one hydrophilic component is water-wettable.
(canceled)
Dependencies are inferred from the claim text.