Drug-delivery systems including drug-delivery device assemblies for attaching to infusion hubs
AssigneeEli Lilly and Company
InventorsDaniel Morris HARTMANN, Gavin Miles MCKEOWN
Life of this patent
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Abstract
The present disclosure relates to a drug-delivery device that is attachable to an infusion set hub that has been pre-inserted into a patient's body. The pre-inserted infusion set hub may be configured to deliver a primary drug such as insulin or an insulin analog. The drug-delivery device may deliver a secondary drug such as a glucagon, an NS AID, or another type of insulin or insulin analog through a cannula of the infusion hub.
Claims40
A drug-delivery device assembly comprising:
- a manifold configured to detachably couple with an infusion hub configured to subcutaneously deliver a primary drug into a patient's body, the manifold defining a fluid channel that connects a proximal surface of the manifold with a distal surface of the manifold;
- a screw cap having an internal surface that, when the screw cap is coupled to the manifold, opposes the distal surface of the manifold;
- and
- a flexible drug reservoir disposed between the distal surface of the manifold and the internal surface of the screw cap, the flexible drug reservoir configured to store a secondary drug,
- wherein the screw cap is configured to couple to the manifold using screw threads such that rotation of the screw cap relative to the manifold causes a distance between the internal surface of the screw cap and the distal surface of the manifold to decrease, thereby compressing the flexible drug reservoir such that the secondary drug is expelled from the reservoir, through the fluid channel in the manifold, and through the infusion hub.
A method for using a drug-delivery device assembly to deliver a secondary drug to a patient's body via an infusion hub positioned on the patient's body for delivering a primary drug, the infusion hub having a hub septum, the method comprising:
- providing the drug-delivery device assembly, the assembly comprising:
- a manifold defining a fluid channel for delivering the secondary drug, the fluid channel being connected to a hub-mate septum on a proximal surface of the manifold, and
- a needle hub separate from the manifold, the needle hub having a staked double-pointed needle with a proximal end and a distal end;
- pushing the needle hub against the proximal surface of the manifold such that the distal end of the double-pointed needle pierces the hub-mate septum of the manifold;
- pushing the manifold and the needle hub against the infusion hub such that the proximal end of the double-pointed needle pierces the hub septum of the infusion hub, thereby providing a passage for the secondary drug to flow from the fluid channel into the infusion hub.
A drug-delivery device assembly comprising:
- a manifold comprising a drug channel, the manifold configured to detachably couple with an infusion hub configured to subcutaneously deliver a primary drug into a patient's body;
- a drug reservoir configured to store a secondary drug, the drug reservoir disposed within the manifold and coupled to the drug channel;
- a drug plunger being movable relative to the drug reservoir;
- and
- a biasing member configured to move away from a loaded state and toward an unloaded state to move the drug plunger relative to the drug reservoir and force the secondary drug from the drug reservoir, through the drug channel, through the infusion hub, and into the patient's body.
A drug-delivery device assembly comprising:
- an infusion hub configured to receive a primary drug from a primary drug-delivery device and deliver the primary drug into a patient's body;
- a manifold configured to detachably couple with the infusion hub, the manifold comprising a drug channel;
- a drug reservoir configured to store a secondary drug, the drug reservoir disposed within the manifold and coupled to the drug channel;
- a drug plunger being movable relative to the drug reservoir;
- and
- a biasing member configured to move away from a loaded state and toward an unloaded state to move the drug plunger relative to the drug reservoir and force the secondary drug from the drug reservoir, through the drug channel, through the infusion hub, and into the patient's body.
Dependencies are inferred from the claim text.