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US 2022/0031844 A1Published application
Semifluorinated alkane compositions comprising omega-3 fatty acid ethyl esters
OwnerJörg Martin MAUDEN, Anja STICHER +3inventors
InventorsJörg Martin MAUDEN, Anja STICHER, Emanuele FRANZINI, Frank LÖSCHER, Michael COORS
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Abstract
The invention provides compositions comprising omega-3 fatty acid ethyl esters, specifically compositions that are based on semifluorinated alkanes. The compositions of the present invention may be topical ophthalmic compositions useful in the treatment of ocular diseases or conditions. The invention further provides kits comprising such compositions.
Claims17
A stable liquid ophthalmic pharmaceutical composition comprising:
- a) at least one omega-3 fatty acid ethyl ester in a total amount of up to 5 wt % based on the total weight of the composition;
- b) a liquid paraffin in a total amount of up to 1 wt % based on the total weight of the composition;
- wherein the at least one omega-3 fatty acid ethyl ester and the liquid paraffin are dissolved in a liquid vehicle comprising a semifluorinated alkane selected from 1-perfluorohexyl-octane (F6H8) or 1-perfluorobutyl-pentane (F4H5).
Dependencies are inferred from the claim text.