Inactivated whole-virus influenza vaccine and method for preparing same
AssigneesDenka Company Limited, National University Corporation Kumamoto University
InventorsRyotaro MITSUMATA, Shogo MISUMI, Naoki KISHIMOTO, Takuma GOTANDA, Nagisa NAKATA
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Abstract
An inactivated whole-virus influenza vaccine may have its antibody-inducing ability is maintained or enhanced and may cause fewer side reactions. A method for preparing an inactivated whole-virus influenza vaccine may use an embryonated chicken egg method, including subjecting a virus solution including a whole influenza virus collected from embryonated chicken eggs to a hypotonic treatment.
Claims7
A method for preparing an inactivated whole-virus influenza vaccine using an embryonated chicken egg technique, the method comprising:
- subjecting a virus solution, comprising whole influenza virus particles collected from embryonated chicken eggs, to a hypotonic treatment.
An inactivated whole-virus influenza vaccine, prepared by an embryonated chicken egg technique, wherein extracellular vesicle components derived from embryonated chicken eggs are reduced.
Dependencies are inferred from the claim text.