Methods and compositions for the treatment of opioid dependence and for the treatment of pain
AssigneeDuke University
InventorsAshwin Patkar, Cynthia Kuhn
Life of this patent
Estimating the term…
Loading patent…
AssigneeDuke University
InventorsAshwin Patkar, Cynthia Kuhn
Estimating the term…
The present invention relates to methods of treating opioid dependence, enhancing the treatment of opioid dependence, treating opioid withdrawal, or alleviating one or more opioid withdrawal symptoms in a subject, preventing or reducing the likelihood of opioid dependence relapse in a subject treated for opioid dependence, reducing the vulnerability of a subject to develop opioid dependence in adulthood following opioid exposure during adolescence, or treating pain in a subject, comprising administering a therapeutically effective amount of a N-methyl-D-aspartate receptor (NMDA) partial agonist to the subject. The present invention further relates to compositions comprising an NMDA partial agonist for use with the aforementioned methods.
(canceled)
(canceled)
(canceled)
A method of treating hyperalgesia in a subject, the method comprising:
(canceled)
(canceled)
(canceled)
A method of reducing the vulnerability of a subject to develop opioid dependence in adulthood following opioid exposure during adolescence, the method comprising:
(canceled)
A composition comprising an NMDA partial agonist and a pharmaceutically acceptable carrier.
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.