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US 2022/0031712 A1Published application
Preparation of a pharmaceutical composition of olodaterol and budesonide
AssigneeCai Gu Huang
InventorsCai Gu Huang, Liang Li
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Abstract
The present invention is directed to a liquid pharmaceutical formulation and a method for administering the pharmaceutical formulation by nebulizing the pharmaceutical formulation with an inhaler. The propellant-free pharmaceutical formulation comprises: (a) active substances selected from budesonide and olodaterol; (b) a solvent; (c) a pharmacologically acceptable solubilizing agent; (d) a pharmacologically acceptable preservative, and (e) a pharmacologically acceptable stabilizer.
Claims22
A liquid, propellant-free pharmaceutical formulation comprising:
- (a) budesonide and olodaterol;
- (b) a solvent;
- and
- (c) a pharmacologically acceptable solubilizing agent;
- wherein the solubilizing agent is selected from the group consisting of a cyclodextrin derivative or a salt thereof, and combinations thereof.
- wherein the pharmaceutical formulation has a pH ranging from about 2.0 to about 6.0.
3 more elements
Dependencies are inferred from the claim text.