US 2022/0031707 A1Published application

Pharmaceutical composition for topical use comprising at least one local anaesthetic substance

AssigneeSociete D'Exploitation De Produits Pour Les Industries Chimiques Seppic

InventorsCatherine BULCOURT, Alice DENIS, Séverine SIGURANI

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Abstract

A pharmaceutical composition for topical use which is in the form of a water-in-oil emulsion including, for 100% of the weight thereof: —from 0.3% to 5% by weight of at least one local anaesthetic substance; —from 60% to 90% by weight of gelled aqueous phase; —from 9.7% to 35% by weight of a fatty phase including at least one oil and an emulsifying system including a combination of at least one emulsifying surfactant selected from the elements of the group consisting of alkylpolyglycoside compositions and alkylpolyglycoside and fatty alcohol compositions, and of at least one emulsifying surfactant selected from the elements of the group consisting of polyglycerol esters, alkoxylated polyglycerol esters, polyglycol polyhydroxystearates, polyglycerol polyhydroxystearates and alkoxylated polyglycerol polyhydroxystearates.

Claims20

Dependent claims

A pharmaceutical composition suitable for topical use which is in the form of an emulsion of water-in-oil type comprising, per 100% of the composition's weight:

from 0.3% to 5% by weight of at least one local anesthetic substance from the family of the amino amides and/or amino esters,
from 60% to 90% by weight of a gelled aqueous phase (A1)
from 9.7% to 35% by weight of a fatty phase (A2) comprising at least one oil and an emulsifying system comprising a combination of at least one emulsifying surfactant (S1) selected from the elements of the group consisting of compositions of alkyl polyglycosides, and compositions of alkyl polyglycosides and of fatty alcohols, and of at least one emulsifying surfactant (S2) selected from the elements of the group consisting of polyglycerol esters, alkoxylated polyglycerol esters, polyglycol polyhydroxystearates, polyglycerol polyhydroxystearates, and alkoxylated polyglycerol polyhydroxystearates.

Dependencies are inferred from the claim text.

Facts

Application: 17/276,315Filed 12 Sep 2019
Priority: FR 185834217 Sep 2018
Published: 3 Feb 2022
Term ends: Not estimatedThe source records don’t support an estimate.

Classification13 codes

A61K 31/5375
Having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines: 1,4-Oxazines, e.g. morpholine
A61K 9/0014
Galenical forms characterised by the site of application: skin, i.e. galenical aspects of topical compositions
A61K 9/06
Medicinal preparations characterised by special physical form: ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
A61K 9/107
Dispersions; Emulsions: emulsions ; Emulsion preconcentrates; Micelles

Family

No related US applications are recorded in the indexed filing history.

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