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AssigneesThe Trustees of Columbia University in the City of New York, The Research Foundation for Mental Hygiene, Inc., Universite Paris-Saclay, Institut National de la Sante et de la Recherche Medicale
InventorsChristine A. Denny, Alain M. Gardier, Denis J. David, Indira Mendez-David, Charlene Faye, Briana K. Chen
Estimating the term…
Methods for prophylactically treating a stress-induced affective disorder or stress-induced psychopathology in a subject are provided. Also provided are methods for inducing and/or enhancing stress resilience in a subject. In certain embodiments, an effective amount of an agonist of the serotonin 4 receptor (5-HT4R), or a pharmaceutically acceptable salt or derivative thereof, is administered to a subject prior to a stressor.
A method for preventing or delaying a stress-induced affective disorder or stress-induced psychopathology and/or inducing and/or enhancing stress resilience in a subject, comprising administering an effective amount of a pharmaceutic composition comprising an agonist of serotonin 4 receptor (5-HT4R), or a pharmaceutically acceptable salt, analog, derivative, or metabolite thereof, to a subject prior to a stressor.
Dependencies are inferred from the claim text.