US 2022/0031627 A1Published application

Peptide coacervates and methods of use thereof

AssigneeNanyang Technological University

InventorsAli Gilles Tchenguise MISEREZ, Yuan PING, Zhi Wei LIM, Bartosz Piotr GABRYELCZYK

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Abstract

The present invention provides for a composition, as disclosed herein, for delivery of an active agent. The composition includes a peptide coacervate, wherein the peptide coacervate includes one or more peptides derived from histidine-rich proteins, and an active agent encapsulated in the peptide coacervate. Further provided are a method for encapsulation of an active agent in a peptide coacervate, a method for delivery of an active agent, and a method for treating or diagnosing a condition or disease in a subject in need thereof.

Claims4

Dependent claims

A method for the encapsulation of an active agent in a peptide coacervate, the method comprising:

(a) providing an aqueous solution of coacervate-forming peptides, wherein the peptides are derived from histidine-rich proteins;
and
(b) combining the aqueous solution of coacervate-forming peptides with the active agent;
and
(c) inducing coacervate formation.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application: 17/506,206Filed 20 Oct 2021
Priority: SG 10201805304Y20 Jun 2018
Published: 3 Feb 2022
Term ends: Not estimatedThe source records don’t support an estimate.

Classification16 codes

A61K 9/5052
Organic macromolecular compounds: proteins, e.g. albumin
A61K 9/5089
Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated…:…
A61K 9/5094
Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated…:…
A61K 31/704
Attached to a carbocyclic compound, e.g. phloridzin: attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin,…

Family

Application16/447,641Division · filed 20 Jun 2019
Application17/506,206Division
US 11,179,342 B2Related patent
US 12,036,327 B2Related patent
US 2019/0388357 A1Published application
US 2022/0031627 A1This patent

From the US filing history. Foreign family members aren’t listed.

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