Catheter for peri-vascular fluid injection

A catheter for fluid delivery through at least two injection needles into tissue outside of the interior wall of a target vessel of a human body, the catheter comprising:

• a catheter body comprising an outer surface, a central axis extending in a longitudinal direction, and a fluid injection lumen;
• at least two guide tubes configured to advance distally and expand outwardly toward the interior wall of the target vessel;
• a support structure;
• at least two injector tubes with distal injection needles, each of the distal injection needles comprising an injection lumen in fluid communication with the fluid injection lumen of the catheter body, the at least two injector tubes with distal injection needles configured to be advanced outwardly, guided by the at least two guide tubes to penetrate the interior wall of the target vessel, the injection needles comprising a distal opening for fluid delivery into the tissue outside of the interior wall of the target vessel;
• and
• a check valve positioned near the proximal end of the fluid injection lumen.

A catheter comprising:

• a catheter body comprising a fluid injection lumen;
• at least one guide tube comprising a distal end, the at least one guide tube moveable between a first position within the catheter body and a second position inclined away from the catheter body, wherein the at least one guide tube is configured to be positioned with the distal end in proximity to an inside wall of a target vessel;
• at least one penetrator comprising an injection lumen in fluid communication with the fluid injection lumen of the catheter body, the at least one penetrator configured to penetrate the inside wall of the target vessel, a portion of the at least one penetrator located coaxially inside of the at least one guide tube;
• a proximal handle configured to advance and retract the at least one guide tube and the at least one penetrator, and
• a check valve in fluid communication with the fluid injection lumen of the catheter body.