Minimally invasive systems and methods for approximating tissue with a suture

A surgical method, comprising:

• inserting an inserter having a suture filament coupled thereto through an incision and through at least a first target tissue, the inserter drawing lengths of a first tail and a second tail of the suture filament through a first opening in the first target tissue;
• decoupling an adjustable loop of the suture filament from the inserter such that the adjustable loop defines an adjustable opening thereof;
• after decoupling the adjustable loop from the inserter, withdrawing the inserter from the first opening in the first target tissue;
• inserting the inserter through a second opening in the first target tissue and through the adjustable opening of the adjustable loop;
• recoupling the adjustable loop to the inserter by collapsing the adjustable loop around the inserter;
• after recoupling the adjustable loop to the inserter, withdrawing the inserter from the second opening in the first target tissue, the inserter drawing lengths of the first and second tails of the suture filament through the second opening;
• and
• after the inserter is withdrawn from the second opening, decoupling the adjustable loop from the inserter.