Method and system for non-invasive blood glucose measurement using signal change of the non-glucose components induced by the presence of glucose
AssigneeSt. Louis Medical Devices, Inc.
InventorZhi Xu
Life of this patent
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Abstract
A method and system for detecting glucose in a biological sample is disclosed. This includes illuminating a biological sample with a light source, collecting transmitted, transflected or reflected light from the sample with a detector, generating spectral data of one or more components in the sample other than glucose in a spectral data analysis device, and analyzing the spectral data of the one or more components, sufficient to provide a glucose measurement from the spectral data of the one or more components other than glucose with the spectral data analysis device.
Claims19
1-21. (canceled)
A method for measuring a blood glucose concentration comprising:
- a) illuminating a biological sample with a light beam from a light generating device;
- and
- b) receiving and analyzing an induced change of a light signal of one or more non-blood glucose components from the sample with a detector,
- wherein the induced change of the light signal is caused by physical or chemical interaction of glucose with the one or more non-blood glucose components;
- wherein the analyzing of the induced change of the light signal comprises:
- generating spectral data, having peaks and valleys, of the one or more non-blood glucose components;
- analyzing spectral data of the one or more blood components, wherein the one or more blood components are non-blood glucose;
- wherein light absorption measured of the one or more non-blood glucose components contains a change of an absorption amount that is induced by an amount of a presence of the blood glucose which is used indirectly determine the concentration of the blood glucose.
A blood glucose concentration measuring device comprising:
- a) a light generating device configured to illuminate a biological sample with a light beam;
- and
- b) a programmable computing device comprising light photocurrent sensors configured to receive and analyze an induced change of a light signal of one or more non-blood glucose components from the sample with a detector,
- wherein the induced change of the light signal is caused by the physical or chemical interaction of glucose with the one or more non-blood glucose components;
- wherein the programmable computing device analyzes the induced change of the light signal by:
- generating spectral data, having peaks and valleys, of the one or more non-blood glucose components;
- analyzing spectral data of the one or more blood components, wherein the one or more blood components are non-blood glucose;
- wherein light absorption measured of the one or more non-blood glucose components contains a change of an absorption amount that is induced by an amount of a presence of the blood glucose which is used to indirectly determine the concentration of the blood glucose.
A system for detecting blood glucose in a biological sample, comprising:
- a) a light generating device configured to illuminate a biological sample comprising a plurality of blood components;
- b) a detector configured to collect transmitted, transflected or reflected light from the biological sample;
- and
- c) a computing device configured to:
- generate spectral data, having peaks and valleys, of the one or more non-blood glucose components;
- analyze spectral data of the one or more blood components, wherein the one or more blood components are non-blood glucose;
- wherein light absorption measured of the one or more non-blood glucose components contains a change of an absorption amount that is induced by an amount of a presence of the blood glucose which is used to indirectly determine the concentration of the blood glucose.
Dependencies are inferred from the claim text.