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US 2022/0025308 A1Published application
Tissue culture platform having multiple well chambers fluidically coupled via microfluidic channels and selector valves
AssigneeNorthwestern University
InventorsHunter B. Rogers, Teresa K. Woodruff
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Abstract
Tissue culture platforms that may be configured for tissue culture or biological cell culture, and methods for use thereof, are described. In general, the tissue culture platforms include multiple well chambers that are fluidically coupled by one or more channels Flow between the different well chambers is controlled via one or more selector valves, enabling a single tissue culture platform that can provide multiple integrated culture subsystems, multiple non-interacting culture subsystems, or combinations thereof.
Claims37
A tissue culture assembly, comprising:
- a base plate;
- a plurality of culture subsystems coupled to the base plate, each culture subsystem comprising:
- a plurality of well chambers;
- a plurality of channels;
- a selector valve fluidically coupling the plurality of well chambers via the plurality of channels;
- and
- wherein the selector valve is operable to modify a fluid path to facilitate exchange of media within a given culture subsystem or between culture subsystems.
4 more elements
A tissue culture assembly, comprising:
- a plurality of culture subsystems, each culture subsystem comprising:
- a plurality of well chambers;
- a plurality of channels;
- a selector valve fluidically coupling the plurality of well chambers via the plurality of channels;
- and
- wherein the selector valve is operable to modify a fluid path to facilitate exchange of media within a given culture subsystem or between culture subsystems.
3 more elements
Dependencies are inferred from the claim text.