Loading patent…
OwnerToshihide Kurihara, Yusaku Katada +1inventors
InventorsToshihide Kurihara, Yusaku Katada, Kazuo Tsubota
Estimating the term…
Provided are a chimeric protein of two types of rhodopsins, an ion-transporting rhodopsin and a G protein-coupled receptor rhodopsin, and a nucleic acid encoding the same, for the prevention and suppression of progression of retinal diseases, the improvement in visual cognitive behavioral functions (e.g., improvement in light-dark determination functions, improvement in bright spot evading functions, and/or crisis avoidance functions), and the enhancement of visual functions (e.g., improvement in visual acuity). The present invention also provides a method for preventing or suppressing the progression of a disease, disorder or symptom of the retina, for improving a visual cognitive behavioral function (e.g., improvement in light-dark determination functions, improvement in bright spot evading functions, and/or crisis avoidance functions), or for enhancing visual functions (e.g., improvement in visual acuity), in a subject, where the method comprises the step of administering an effective amount of a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin to the subject.
A composition for preventing or suppressing the progression of a disease, disorder or symptom of the retina, the composition comprising a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin.
A composition for improving a visual cognitive behavioral function, the composition comprising a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin.
A composition for enhancing a visual function, the composition comprising a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin.
A composition for preventing or suppressing the progression of a disease, disorder or symptom of the retina, the composition comprising a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin.
A composition for improving a visual cognitive behavioral function, the composition comprising a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin.
A composition for enhancing a visual function, the composition comprising a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin.
A nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, wherein the chimeric protein is for preventing or suppressing the progression of a disease, disorder or symptom of the retina.
A nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, wherein the chimeric protein is for improving a visual cognitive behavioral function.
A nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, wherein the chimeric protein is for enhancing a visual function.
A chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, wherein the chimeric protein is for preventing or suppressing the progression of a disease, disorder or symptom of the retina.
A chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, wherein the chimeric protein is for improving a visual cognitive behavioral function.
A chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, wherein the chimeric protein is for enhancing a visual function.
A method for preventing or suppressing the progression of a disease, disorder or symptom of the retina in a subject in need thereof, the method comprising administering an effective amount of a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin to the subject.
A method for improving a visual cognitive behavioral function in a subject in need thereof, the method comprising administering an effective amount of a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin to the subject.
A method for enhancing a visual function in a subject in need thereof, the method comprising administering an effective amount of a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin to the subject.
A method for preventing or suppressing the progression of a disease, disorder or symptom of the retina in a subject in need thereof, the method comprising administering an effective amount of a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin to the subject.
A method for improving a visual cognitive behavioral function in a subject in need thereof, the method comprising administering an effective amount of a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin to the subject.
A method for enhancing a visual function in a subject in need thereof, the method comprising administering an effective amount of a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin to the subject.
A pharmaceutical composition comprising a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, for preventing or suppressing the progression of a disease, disorder or symptom of the retina.
A pharmaceutical composition comprising a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, for improving a visual cognitive behavioral function.
A pharmaceutical composition comprising a nucleic acid encoding a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, for enhancing a visual function.
A pharmaceutical composition comprising a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, for preventing or suppressing the progression of a disease, disorder or symptom of the retina.
A pharmaceutical composition comprising a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, for improving a visual cognitive behavioral function.
A pharmaceutical composition comprising a chimeric protein of an ion-transporting receptor rhodopsin and a G protein-coupled receptor rhodopsin, for enhancing a visual function.
A nucleic acid being characterized by one or more of:
Dependencies are inferred from the claim text.