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US 2022/0023250 A1Published application
Isopropylcarbonate benzoyl peroxide compositions and methods of use
AssigneeGalderma Holding SA
InventorsKarine Nadau-Fourcade, Jean-Christophe Buge
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Abstract
Described herein are compositions comprising (i) Isopropylcarbonate Benzoyl Peroxide, (ii) an opacifier, and (iii) and a preserving agent that have good physical, chemical and microbiological stability and corresponding methods of use.
Claims20
A topically applicable composition comprising:
- i) Isopropylcarbonate Benzoyl Peroxide;
- ii) an opacifier;
- and
- iii) a preserving agent.
1 more element
A method for producing an Isopropylcarbonate Benzoyl Peroxide aqueous gel, which method comprises the steps of:
- solubilizing a sequestering agent in aqueous solution to produce the main phase;
- preparing a disaggregation medium comprising Isopropylcarbonate Benzoyl Peroxide by dispersing Isopropylcarbonate Benzoyl Peroxide, propylene glycol, glycerol and liquid wetting surfactant in water to produce medium A;
- and
- adding titanium dioxide to the main phase;
- adding a first portion of gelling agent to the main phase;
- adding medium A to the main phase;
- adding of phenoxyethanol to the main phase;
- solubilizing docusate sodium in water to provide solubilized docusate sodium followed by addition of the solubilized docusate sodium to the main phase by gentle agitation;
- and
- adding a second portion of gelling agent to the main phase,
- whereby a gel is formed.
8 more elements
Dependencies are inferred from the claim text.