Plant tissue-derived nanofibres
AssigneePsigryph Inc.
InventorsGopinadhan PALIYATH, Krishnaraj TIWARI, Renu CHANDRASEKARAN, Julieta CORREA-BETANZO, Priya PADMANABHAN, Jayasankar SUBRAMANIAN
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Abstract
Provided herein are nanofibres including self-assembled cellular components derived from a homogenized plant tissue. Methods for preparing such nanofibres, as well as uses thereof in the treatment or prevention of diseases or disorders in a subject and/or as delivery vehicles are also described.
Claims93
A nanofibre comprising self-assembled cellular components derived from a homogenized plant tissue, the cellular components comprising one or more structural carbohydrates or cleavage products thereof, wherein lipids and polyphenols are not a structural components of the nanofibre.
A method for preparing nanofibres from homogenized plant tissue, said method comprising:
- preparing a homogenized plant tissue in solution having low polyphenol content, comprising cellular components liberated from the plant tissue;
- removing debris from the homogenized plant tissue, if present;
- and
- optionally, dialyzing the homogenized plant tissue to remove non-complexed compounds, or removing the non-complexed compounds by size exclusion,
- thereby providing a solution comprising the nanofibres which are formed by self-assembly of the cellular components.
A method for preparing a nanofibre from homogenized plant tissue, said method comprising:
- preparing a homogenized plant tissue in solution having low polyphenol content, comprising cellular components liberated from the plant tissue;
- removing debris from the homogenized plant tissue, if present;
- allowing the nanofibre to form by self-assembly of the cellular components;
- and
- freeze-drying, spray-drying, or nanospray drying to form a powder comprising the nanofibre.
Dependencies are inferred from the claim text.