Functionalised Nanoparticle
AssigneeRadetec Pty Ltd
InventorsZhiyuan LI, Fabio LISI
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Abstract
A functionalised nanoparticle that is at least in part coated by a polymer, wherein the polymer comprises charged and uncharged groups at a ratio ranging from 4:1 to 1:4 and the functionalised nanoparticle is conjugatable or can be functionalised to conjugate with a biomolecule.
Claims18
A functionalised nanoparticle that is at least in part coated by a polymer, wherein the polymer comprises charged and uncharged groups at a ratio ranging from 4:1 to 1:4 and the functionalised nanoparticle is conjugatable or can be functionalised to conjugate with a biomolecule.
A method of producing a functionalised nanoparticle comprising:
- providing a nanoparticle;
- providing a polymer comprising charged and uncharged groups at a ratio ranging from 4:1 to 1:4;
- and
- mixing the nanoparticle and the polymer to form the functionalised nanoparticle that is at least in part coated by the polymer and that is conjugatable or can be functionalised to conjugate to a biomolecule.
A method of producing a nanoparticle-biomolecule conjugate comprises:
- providing a nanoparticle;
- providing a polymer comprising charged and uncharged groups at a ratio ranging from 4:1 to 1:4;
- mixing the nanoparticle and the polymer to form a functionalised nanoparticle which is at least in part coated by the polymer;
- and
- reacting the functionalised nanoparticle with a biomolecule to form the nanoparticle-biomolecule conjugate, wherein the nanoparticle-biomolecule conjugate can be bonded to a target analyte.
Dependencies are inferred from the claim text.