Cd47 antibody, preparation method therefor and uses thereof

A heavy chain variable region of an antibody, wherein the heavy chain variable region has a complementarity determining region CDR selected from the group consisting of:

• VH-CDR1 shown in SEQ ID NO.10n+3,
• VH-CDR2 shown in SEQ ID NO.10n+4, and
• VH-CDR3 shown in SEQ ID NO.10n+5;
• wherein, each n is independently 0, 1, 2, 3, 4, 5, 6, or 7;
• wherein any one of the above amino acid sequences further comprises a derivative sequence which is obtained through optional addition, deletion, modification and/or substitution of at least one amino acid and is capable of retaining CD47 binding affinity.