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US 2022/0017534 A1Published application
In-flow photooxygenation of aminothienopyridinones generates novel ptp4a3 phosphatase inhibitors
AssigneeUniversity of Virginia Patent Foundation
InventorsJohn S. Lazo, Elizabeth Sharlow, Peter Wipf, Nikhil Tasker, Ettore Rastelli
Life of this patent
Estimating the term…
Abstract
The disclosure provides compounds that inhibit protein tyrosine phosphatase, such as protein tyrosine phosphatase 4 A3 (PTP4A3). The disclosure also provides pharmaceutical compositions, uses, and methods of using the compounds, such as in the treatment of cancers.
Claims9
A compound, or a pharmaceutically acceptable salt thereof, selected from the following table:
- 3
- 15
- 9a
- 9b
- 9c
- 9d
- 9e
- 9f
- 9g
- 9h
- 9i
- 9j
- 9k
- 9l
- 9m
- 9n
- 9o
- 9q
- 9p
- NRT- 892-04
17 more elements
-10. (canceled)
Dependencies are inferred from the claim text.