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US 2022/0017468 A1Published application
ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR IMBALANCE
AssigneeDermavant Sciences GmbH
InventorsChanna K. JAYAWICKREME, Susan H. SMITH, Cunyu ZHANG, William ZUERCHER
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Abstract
The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.
Claims11
A compound which is 2-isopropyl-5-(isoquinolin-3-yl)benzene-1,3-diol of the formula:
- or a pharmaceutically acceptable salt, solvate or hydrate thereof.
-26. (canceled)
Dependencies are inferred from the claim text.