Isoform nell-1 peptide
AssigneeThe Regents of the University of California
InventorsKang TING, B. Chia SOO
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Abstract
This application is drawn to a method of using an isoform NELL-1 peptide, and compositions thereof for bone formation or for treating, preventing, or ameliorating osteoporosis.
Claims20
A method of increasing bone formation or regeneration at or near a bone fracture site in a subject in need thereof, the method comprising increasing the concentration of an ISN-1 gene product at the bone fracture site.
A method of treating, preventing or ameliorating osteoporosis by administering to a bone tissue at a pre-selected site an effective amount of an ISN-1, a related agent, or a combination thereof.
A method of administration of an ISN-1 agent, an ISN-1-related agent, or a combination thereof, for treatment of osteoporosis to a patient in need thereof, comprising the steps of:
- diagnosing a patient with osteoporosis;
- pre-selecting a tissue site in need of osteoporosis amelioration;
- making in incision proximate to the tissue in need of osteoporosis amelioration;
- and
- delivering, via the incision, a therapeutically effective amount of an ISN-1 agent, an ISN-1-related agent, or a combination thereof.
Dependencies are inferred from the claim text.