Pharmaceutical compositions
AssigneeAdeptio Pharmaceuticals Limited
InventorsAndrew John DUFFIELD, Anant PANDYA
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Abstract
The invention provides (+)-α-dihydrotetrabenazine succinate salt. Also provided are (+)-α-dihydrotetrabenazine succinate salt for use in medicine, pharmaceutical compositions comprising (+)-α-dihydrotetrabenazine succinate salt and a pharmaceutically acceptable excipient and the uses of (+)-α-dihydrotetrabenazine succinate salt as a VMAT2 receptor antagonist and in the treatment of a movement disorder such as Tourette's syndrome. The invention further provides a method for preparing the (+)-α-dihydrotetrabenazine succinate salt.
Claims20
A method of preparing (+)-α-dihydrotetrabenazine succinate salt which comprises mixing (+)-α-dihydrotetrabenazine free base and succinic acid together with a solvent, allowing time for (+)-α-dihydrotetrabenazine succinate salt to form and isolating the succinate salt.
Dependencies are inferred from the claim text.