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US 2022/0016103 A1Published application
Methods of using factor b inhibitors
AssigneeNovartis AG
InventorsIrina BALTCHEVA, Peter END, Julie Marie-Pomme Gabrielle MILOJEVIC
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Abstract
Described herein are methods of treating paroxysmal nocturnal hemoglobinuria (PNH) with the Factor B inhibitor LNP023 or a pharmaceutically acceptable salt thereof, e.g. LNP023 hydrochloride.
Claims20
A method of treating paroxysmal nocturnal hemoglobinuria (PNH) in a subject in need thereof, the method comprising orally administering to the subject LNP023 or a pharmaceutically acceptable salt thereof, at a dose of about 200 mg twice daily (b.i.d.), to thereby treat the subject (wherein the dosing amount refers to the anhydrous free base of LNP023 hydrochloride).
Dependencies are inferred from the claim text.