System and method for determining a health condition of the liver of a subject

A method for determining a health condition of the liver of a subject, by means of a system comprising:

• an elastography device configured to measure at least one mechanical parameter relative to the propagation of shear waves in liver,
• a blood-test reader and a blood-test disposable associated to the blood test reader, the blood-test disposable being configured to receive a capillary blood sample and to be inserted in the blood test reader, the blood-test reader being configured to determine a concentration of at least one liver enzyme in said blood sample, wherein:
• the blood-test disposable comprises:
• a capillary tube for collecting said blood sample from said finger, and
• reagents, appropriate to detect said at least one liver enzyme in said blood sample, and wherein
• the blood-test reader is operatively connected to the elastography device, and
• a control and processing system, comprising at least a processor and a memory, configured to control the elastography device and the blood test reader, the method comprising the following steps:
• S100—measuring a value of said mechanical parameter using the elastography device, for the liver of the subject under examination,
• S1—acquiring by the control and processing system the value of said at least one mechanical parameter, measured by the elastography device,
• S200—collecting a capillary blood sample from the subject by means of said capillary tube, and then introducing the blood-test disposable in the blood-test reader,
• S2—acquiring by the control and processing system a value of a concentration of said at least one liver enzyme in a blood sample collected from the subject, measured by the blood test reader, and
• S3—determining by the control and processing system a health condition of the liver of the subject, taking into account both the value of said at least one mechanical parameter and the value of the concentration of said at least one liver enzyme, said health condition being represented by a health or disease stage identified among different stages of a given health condition classification, or being represented by a value of a benchmark parameter taking into account both the value of said at least one mechanical parameter and the value of the concentration of said at least one liver enzyme, or being represented both by said health or disease stage and by said value of said benchmark parameter, and outputs data representative of said health condition.