In vitro diagnostic assay methods
AssigneeUCL Business PLC
InventorsBen MILLER, Leonard BEZINGE, Peter DOBSON, Gavin DOLD, John MORTON, Rachel MCKENDRY
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Abstract
An in vitro diagnostic assay method, comprising: providing a sample which may comprise target analyte(s); contacting the sample with a fluorescent label whose fluorescence can be externally modulated, such that the fluorescent label is associated with target analyte(s), if present, to form a fluorescent label-analyte complex; and detecting the fluorescent label-analyte complex; and device, kit and solid phase for performing an in vitro diagnostic assay method.
Claims25
An in vitro diagnostic assay method, comprising:
- providing a sample which may comprise target analyte(s);
- contacting the sample with a fluorescent label whose fluorescence can be externally modulated, such that the fluorescent label is associated with target analyte(s), if present, to form a fluorescent label-analyte complex;
- and
- detecting the fluorescent label-analyte complex.
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A device for performing an in vitro diagnostic assay, wherein said device comprises:
- a solid phase according to claim 23;
- an excitation light source;
- a fluorescence modulator;
- and
- a fluorescence detector.
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A kit for performing an in vitro diagnostic assay, wherein said kit comprises:
- a solid phase comprising a fluorescent label whose fluorescence can be externally modulated, or
- a solid phase and a separate liquid suspension or solution comprising a fluorescent label whose fluorescence can be externally modulated.
A solid phase comprising a fluorescent label whose fluorescence can be externally modulated, wherein said solid phase is selected from a multiwell plate, beads, column, photonic device, microfluidic chip or capillary bed for microfluidic flow assay.
Dependencies are inferred from the claim text.