Method to obtain low triterpene/triterpenoid-containing natural rubber latex

Method according to any one of the preceding claims, wherein the at least one oxidosqualene cyclase is selected from the group consisting of oxidosqualene cyclase 1 according to SEQ ID NO:

• 4, the oxidosqualene cyclase 2 according to SEQ ID NO:
• 6, the oxidosqualene cyclase 3 according to SEQ ID NO:
• 8, the oxidosqualene cyclase 4 according to SEQ ID NO:
• 10, the oxidosqualene cyclase 5 according to SEQ ID NO:
• 12, the oxidosqualene cyclase 6 according to SEQ ID NO:
• 14, the oxidosqualene cyclase 7 according to SEQ ID NO:
• 16, the oxidosqualene cyclase 8 according to SEQ ID NO:
• 18, the lupeol synthase according to SEQ ID NO:
• 20 and an amino acid sequence being at least 60%, 70%, 80%, 90%, 95% or 99% identical to SEQ ID NOs:
• 4, 6, 8, 10, 12, 14, 16, 18 or 20,
• preferably wherein the at least one oxidosqualene cyclase is selected from the group consisting of the oxidosqualene cyclase 1 according to SEQ ID NO:
• 4, the oxidosqualene cyclase 2 according to SEQ ID NO:
• 6, the oxidosqualene cyclase 3 according to SEQ ID NO:
• 8 and the oxidosqualene cyclase 5 according to SEQ ID NO:
• 12 and an amino acid sequence being at least 60%, 70%, 80%, 90%, 95% or 99% identical to SEQ ID NOs:
• 4, 6, 8 or 12,
• more preferably wherein the at least one oxidosqualene cyclase is the oxidosqualene cyclase 1 according to SEQ ID NO:
• 4 or an amino acid sequence being at least 60%, 70%, 80%, 90%, 95% or 99% identical thereto.

RNAi being specifically directed against a mRNA transcript of at least one oxidosqualene cyclase,

• preferably wherein the RNAi comprises or consists of a nucleotide sequence according to SEQ ID NO:
• 1 and/or comprises or consists of a nucleotide sequence according to SEQ ID NO:
• 2 and/or comprises or consists of a nucleotide sequence being at least 60%, 70%, 80%, 90%, 95% or 99% identical to SEQ ID NO:
• 1 or SEQ ID NO:
• 2,
• for use in a method of reducing or eliminating the content of triterpenes and/or triterpenoids of latex or rubber from a laticiferous plant or part thereof.