Compositions and methods for controlling arthropod parasite and pest infestations
OwnerAlex INBERG, Mahak KAPOORinventors
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Abstract
This application provides and discloses anti-parasitic, anti-pest or insecticidal nucleic acid molecules and their calmodulin target genes for the control of arthropod parasites and pests. In particular, this application provides and discloses insecticidal nucleic acid molecules that target Varroa calmodulin gene sequences. This application further provides methods and compositions for the control and treatment of parasites and pests in Apis mellifera (honey bee) hives.
Claims22
1-48. (canceled)
A selective insecticide composition comprising a nucleic acid molecule, wherein said nucleic acid molecule is a double-stranded RNA (dsRNA) comprising a sequence selected from SEQ ID NOs:
- 90-92, and wherein the nucleic acid molecule does not comprise a sequence of 22 or more contiguous nucleotides that are 100% identical or complementary to a gene sequence of a non-target organism.
The selective insecticide composition of claim 1, wherein said dsRNA comprises the sequence of SEQ ID NO:
- 91.
A selective insecticide composition comprising a nucleic acid molecule, wherein said nucleic acid molecule is a double-stranded RNA (dsRNA) comprising a sequence selected from SEQ ID NOs:
- 90-92, and wherein the nucleic acid molecule does not comprise a sequence of 19 or more contiguous nucleotides that are 100% identical or complementary to a gene sequence of Apis mellifera.
A method of selectively treating an arthropod species for parasites, comprising delivering an effective amount of a nucleic acid molecule, to said arthropod species, wherein said nucleic acid molecule is a dsRNA comprising a sequence selected from SEQ ID NOs:
- 90-92, and wherein the nucleic acid molecule does not comprise a sequence of 19 or more contiguous nucleotides that are 100% identical or complementary to a gene sequence of a Apis mellifera.
Dependencies are inferred from the claim text.