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US 2022/0010303 A1Published application
Direct-to-library methods, systems, and compositions
AssigneeKarius, Inc.
InventorsSivan BERCOVICI, Lily BLAIR, Timothy A. BLAUWKAMP, Peter J. EUGSTER, David K. HONG, Trupti KAWLI, Michael J. ROSEN, Damek SPACEK, Igor D. VILFAN
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Abstract
Provided herein are direct-to-library methods, systems, and compositions.
Claims47
A method of preparing a nucleic acid library from an initial sample, comprising:
- (a) adding one or more process control molecules to the initial sample to provide a spiked initial sample;
- and
- (b) generating a nucleic acid library from the spiked initial sample;
- wherein nucleic acids used to generate the nucleic acid library are not extracted from the initial sample before preparing the nucleic acid library.
1 more element
A method of preparing a nucleic acid library from an initial sample, comprising generating a nucleic acid library from the said initial sample;
- wherein nucleic acids used to generate the nucleic acid library are not extracted from the initial sample before preparing the nucleic acid library.
Dependencies are inferred from the claim text.