Subtilase variants and polynucleotides encoding same

A subtilase variant comprising a set of alterations selected from the group consisting of:

• (a) X167A+R170S+A194P and one or more substitutions selected from the group consisting of X59D, X62D, X76D, X104T, X120D, X133P, X141N, X156D, X163G, X209W, X228V, X230V, X238E, X261D, and X262E;
• (b) *99aE and one or more substitutions selected from the group consisting of X21D, X59D, X101H, X120D, X156D, X163G, X194P, X195E, X209W, X238E, X256D, X261D, and X262E;
• (c) X62D and one or more substitutions selected from the group consisting of X101H, X104T, X156D, X163G, X170S, X170L, X209W, X238E, X245R and X262E;
• (d) X62D+X245R+X248D and one or more substitutions selected from the group consisting of X156D, X163G, X163K, X170S, X209W, and X262E;
• (e) X170L, X170N or X170S and one or more substitutions selected from the group consisting of X57P, X167A, X172E, X206E,
• (f) X99D and one or more substitutions selected from the group consisting of *97aN, *98aA, X98T, X261D, and X262Q, wherein
• (i) the positions correspond to the positions of the polypeptide of SEQ ID NO:
• 2;
• (ii) the variant has protease activity;
• and
• (iii) the variant has at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% but less than 100% sequence identity to the polypeptide of SEQ ID NO:
• 1 or 2.