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US 2022/0009997 A1Published application
Anti-vegf protein compositions and methods for producing the same
AssigneeRegeneron Pharmaceuticals, Inc.
InventorMatthew Franklin
Life of this patent
Estimating the term…
Abstract
The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
Claims24
A polypeptide having an isolated amino acid sequence comprising at least 70% sequence identity over a full length of said isolated amino acid sequence as set forth in the group consisting of SEQ ID NO.:
- 2, SEQ ID NO.:
- 3, SEQ ID NO.:
- 4, SEQ ID NO.:
- 5, SEQ ID NO.:
- 6, SEQ ID NO.:
- 7, SEQ ID NO.:
- 8, SEQ ID NO.:
- 9, SEQ ID NO.:
- 10, SEQ ID NO.:
- 11, SEQ ID NO.:
- 12, SEQ ID NO.:
- 13, SEQ ID NO.:
- 14, SEQ ID NO.:
- 15 and SEQ ID NO.:
- 16, wherein said polypeptide excludes IdeS as set forth in SEQ ID NO.:
- 1.
13 more elements
An isolated nucleic acid molecule encoding a polypeptide with an amino acid sequence as set forth in the group consisting of SEQ ID NO.:
- 2, SEQ ID NO.:
- 3, SEQ ID NO.:
- 4, SEQ ID NO.:
- 5, SEQ ID NO.:
- 6, SEQ ID NO.:
- 7, SEQ ID NO.:
- 8, SEQ ID NO.:
- 9, SEQ ID NO.:
- 10, SEQ ID NO.:
- 11, SEQ ID NO.:
- 12, SEQ ID NO.:
- 13, SEQ ID NO.:
- 14, SEQ ID NO.:
- 15 and SEQ ID NO.:
- 16, wherein said polypeptide excludes IdeS as set forth in SEQ ID NO.:
- 1.
13 more elements
An isolated amino acid comprising a parental amino acid sequence defined by SEQ ID NO.:
- 1 with asparagine residues at one or more positions of 87, 130, 182 or 274 mutated to an amino acid other than asparagine.
Dependencies are inferred from the claim text.