Novel urea 6,7-dihydro-4h-pyrazolo[4,3-c]pyridines active against the hepatitis b virus (hbv)

A compound of Formula I

• in which
• R1 is phenyl or pyridyl, optionally substituted once, twice, or thrice by halogen, C1-C4-alkyl, C3-C6-cycloalkyl, C1-C4-haloalkyl or C≡N
• R2 is H or methyl
• R3 is H or C1-C4-alkyl, wherein C1-C4-alkyl is optionally substituted once, twice, or thrice with deuterium, halogen or C≡N
• R4 is selected from the group consisting of C1-C2-alkyl with the proviso that R4 is connected to R3, C1-C2-alkyl-O—C1-C4-alkyl, C1-C2-hydroxyalkyl, C1-C2-alkyl-O—C1-C4-haloalkyl, C1-C2-alkyl-O—C3-C6-cycloalkyl, C1-C2-alkyl-S-C1-C4-alkyl, C1-C2-alkyl-SO2-C1-C4-alkyl, C≡N, C1-C2-alkyl-C3-C7-heterocycloalkyl, C1-C2-alkyl-O—C(═O)(C3-C7-cycloalkyl)NH2, C1-C2-alkyl-O—C(═O)(C1-C13-alkyl)NH2, C3-C7-heterocycloalkyl, aryl and heteroaryl, wherein C3-C7-heterocycloalkyl, aryl or heteroaryl are optionally substituted once, twice or thrice with halogen, NH2 or C1-C6-alkylR3 and R4 are optionally connected to form a five, six or seven membered heterocycloalkyl ring, said heterocycloalkyl ring is unsubstituted or substituted once, twice or thrice with halogen, carboxy, OH, C1-C4-alkoxy, OCF3, OCHF2 or C≡N
• X is 0, CH2, or NR11
• m is 0, 1 or 2
• R11 is H or C1-C4-alkyl
• or a pharmaceutically acceptable salt thereof
• or a solvate or a hydrate of a compound of Formula I or the pharmaceutically acceptable salt thereof
• or a prodrug of a compound of Formula I or a pharmaceutically acceptable salt or a solvate or a hydrate thereof.