Polymer system for securing implants in syringe needles
AssigneeAllergan, Inc.
InventorsLon T. Spada, Alazar N. Ghebremeskel, Michael R. Robinson
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Abstract
Disclosed herein are methods of delivering implants to a target organ with an implant administration device, where the implant administration device includes a polymer retainer. Methods of making polymer retainers and methods of securing an implant within an implant administration device using a polymer retainer are also disclosed herein.
Claims17
-16. (canceled)
A method for securing an implant within an implant administration device comprising:
- providing an implant administration device comprising an aperture;
- providing a polymer;
- providing an implant;
- inserting the implant within the implant administration device, so that the implant is contained within the implant administration device;
- and
- coating or plugging the aperture of the implant administration device with the polymer to form a polymer retainer, thus securing the implant within the implant administration device.
The method of claim 1, wherein the implant administration device is a syringe needle, the syringe needle comprising a sharp distal tip.
The method of claim 2, wherein the polymer is hydroxypropyl methyl cellulose (“HPMC”).
The method of claim 3, wherein the sharp distal tip of the syringe is coated with the polymer.
The method of claim 3, wherein the sharp distal tip is not coated with the polymer.
The method of claim 3, wherein the syringe needle has a size selected from the group consisting of 22-gauge, 25-gauge, 27-gauge or 28-gauge.
The method of claim 3, wherein the implant is an intraocular implant.
The method of claim 3, wherein the polymer retainer increases the actuation force necessary to expel the implant secured within the implant administration device by about 1% to about 25%, compared to actuation force necessary to expel the implant without the polymer retainer present.
A method for delivering an implant within an implant administration device to a patient in need thereof comprising:
- providing an implant administration device comprising an aperture;
- providing a polymer comprising HPMC;
- providing an implant;
- inserting the implant within the implant administration device, so that the implant is contained within the implant administration device;
- coating or plugging the aperture of the implant administration device with the polymer to form a polymer retainer, thus securing the implant within the implant administration device;
- inserting the implant administration device containing the implant and the polymer retainer into an organ of a patient;
- and
- administering the implant into the organ of the patient.
The method of claim 9, wherein the implant administration device is a syringe needle, the syringe needle comprising a sharp distal tip.
The method of claim 10, wherein the polymer is provided in a solution or gel form.
The method of claim 11, wherein the sharp distal tip of the syringe is coated with the polymer.
The method of claim 11, wherein the sharp distal tip is not coated with the polymer.
The method of claim 11, wherein the syringe needle has a size selected from the group consisting of 22 gauge, 25 gauge, 27 gauge, or 28 gauge.
The method of claim 11, wherein the implant is an intraocular implant.
The method of claim 11, wherein the polymer retainer increases the actuation force necessary to expel the implant secured within the implant administration device by about 1% to about 25%, compared to actuation force necessary to expel the implant without the polymer retainer present.
Dependencies are inferred from the claim text.