A method of mimicking benefits of dietary restriction by transiently upregulating er stress response
AssigneeNational Institute of Immunology
InventorsArnab MUKHOPADHYAY, Kausik CHAKRABORTY, Latika MATAI
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Abstract
A role of molecular mechanisms determine the longevity of an organism, particularly, method of mimicking benefits of dietary restriction by transiently upregulating endoplasmic stress response.
Claims12
A method of inducing an early and transient upregulation of Unfolded Protein Response (UPRER) in a subject by either generating a nutrient restriction or administering pharmaceutical reagent, wherein said method mimics the pro-longevity effects of the dietary restriction (DR).
A pharmaceutical reagent or dietary restriction for inducing an early and transient upregulation of Unfolded Protein Response (UPRER) in a subject.
A method of applying a pharmaceutical reagent or dietary restriction for inducing an early and transient upregulation of Unfolded Protein Response (UPRER) in a subject.
A kit claim comprising a pharmaceutical reagent and instruction manual for performing the method of inducing an early and transient upregulation of Unfolded Protein Response (UPRER) in a subject.
Dependencies are inferred from the claim text.