Wound dressing having microbe resistant micropatterened surface

A method of forming a wound dressing, comprising:

• forming a negative mold having a top surface with a plurality of denticle cavities formed in the surface and extending in a body of the negative mold, each denticle cavity of the plurality of denticle cavities configured to form a denticle having:
• a base portion at an opening in the top surface of the negative mold, and having a front and a rear;
• a denticle body that extends from the base portion to the rear beyond the rear of the base portion and is separated from the top surface of the negative mold;
• placing a fabric layer on the top surface of the negative mold;
• after placing the fabric layer, pouring a dressing material onto the mold that fills in the plurality of denticle cavities to a selected height above the top surface of the negative mold;
• curing the dressing material to produce a cured wound dressing, wherein the fabric is thereby contained in the cured wound dressing;
• and
• removing the cured wound dressing from the negative mold, wherein the cured would dressing includes a plurality of denticles corresponding to the plurality of denticle cavities.
• prior to pouring the dressing material, providing a fabric on the top surface, wherein pouring the dressing material comprises pouring the dressing material over the fabric, wherein the fabric is thereby contained in the cured wound dressing

A method of forming a wound dressing, comprising:

• forming a negative mold having a top surface with a plurality of denticle cavities formed in the surface and extending in a body of the negative mold, each denticle cavity of the plurality of denticle cavities configured to form a denticle having:
• a base portion at an opening in the top surface of the negative mold, and having a front and a rear;
• a denticle body that extends from the base portion to the rear beyond the rear of the base portion and is separated from the top surface of the negative mold;
• pouring a dressing material onto the mold that fills in the plurality of denticle cavities to a selected height above the top surface of the negative mold;
• while pouring the dressing material, applying vibration to the negative mold and continuing to apply the vibration for a period of time after pouring the dressing material to drive air out of the denticle cavities, thereby allowing the denticle cavities to fill with the dressing material;
• curing the dressing material to produce a cured wound dressing;
• and
• removing the cured wound dressing from the negative mold, wherein the cured would dressing includes a plurality of denticles corresponding to the plurality of denticle cavities.