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US 2022/0007645 A1Published application
Aqueous solutions of poorly soluble active ingredients using polyalkyoxylated amino alcohols
AssigneeDow Global Technologies LLC
InventorsMichael P. Tate, Thomas H. Kalantar, Michael L. Tulchinsky, David Brennan, Adam H. Xiong
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Abstract
Disclosed is the use a polyalkoxylated amino alcohol to solubilize active compounds that are poorly soluble in water, including particularly agricultural actives or pharmaceutical actives. Also disclosed are compositions comprising such actives, water and the polyalkoxylated aminoalcohol.
Claims15
A composition comprising biologically active compound that is insoluble or poorly soluble in water and a polyalkoxylated amino alcohol of the formula
- where Ri, R2, R3, and R4 are independently selected from alkyl, alkenyl, aryl, aralkyl, or heterocyclic groups having 1-25 carbons, R5 is a divalent alkyl, alkenyl, aryl, aralkyl, or heterocyclic group having 4-25 carbons, and where each AO is a polyoxyalkylene chain having oxypropylene (PO) and oxyethylene (EO) groups, where m is the average number of PO groups per AO group and n is the average number of the average number of EO groups per AO group, and m is at least 1, n is at least 2, and m+n is at least 20 no more than 400, wherein the composition is solid or comprises water.
Dependencies are inferred from the claim text.