Compositions and methods for delivery of aav
AssigneeVoyager Therapeutics, Inc.
InventorsGiridhar Murlidharan, Dinah Wen-Yee Sah, Holger Patzke, Todd Carter, Jinzhao Hou, Kei Adachi, Amy Ren
Life of this patent
Estimating the term…
Abstract
The disclosure provides compositions and methods for the preparation, manufacture, formulation and therapeutic use of adeno-associated virus (AAV) particles for the prevention and/or treatment of diseases.
Claims96
An adeno-associated viral (AAV) particle comprising a capsid and a viral genome, wherein said capsid penetrates the blood brain barrier following delivery of the AAV particle, wherein the capsid comprises VOY701.
An AAV particle comprising a capsid and a viral genome, wherein said capsid penetrates the blood brain barrier following delivery of the AAV particle, wherein the amino acid sequence of the capsid is at least 95% identical to SEQ ID NO:
- 1829.
Dependencies are inferred from the claim text.