Lesion localization in an organ

Abstract

The invention relates to a computerized method (200) for localizing a lesion in an organ of a subject, comprises performing: a first image registration operation (400) for determining a rigid transformation matrix based on alignment of a two-dimensional ultrasound (2D-US) image representation (116) and a three-dimensional computed tomography (3D-CT) image representation (120) of the organ, the 2D-US image representation (116) acquired from a transducer probe (114); a second image registration operation (500) for refining the rigid transformation matrix based on image feature descriptors of the 2D-US and 3D-CT image representations (116, 120); and a localization operation (600) for localizing the lesion relative to the transducer probe (114) based on the refined rigid transformation matrix and a 3D-CT position of the lesion in the 3D-CT image representation (120). A system for performing the method is also disclosed herein. The system may further comprise an ablation apparatus for radio frequency ablation of the lesion.

Dependencies are inferred from the claim text.