Sensitivity marker for antibody-drug conjugate

A method for identifying a subject to whom a medicament containing an anti-hTROP2 antibody is to be given, wherein the subject is a human patient suffering from a cancer, the method comprising:

• 1) obtaining a biological sample from the human patient diagnosed as suffering from a cancer;
• 2) evaluating an amount of expression of the hTROP2 gene at mRNA level in the biological sample;
• 3) evaluating an amount of expression of the SLFN11 gene at mRNA level in the biological sample, wherein the biological sample is one that is determined to have a high amount of expression of the hTROP2 gene;
• and
• 4) identifying the human patient who provided the biological sample, wherein the biological sample is one that is determined to have a high amount of expression of the SLFN11 gene, as a subject to whom a medicament containing an anti-hTROP2 antibody is to be given.