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AssigneeShanghai Mental Health Center (Shanghai Psychological Counselling Training Center)
InventorsTao Wang, Shifu Xiao, Haining He
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Diagnostic markers for mild cognitive impairment (MCI) due to Alzheimer's disease (AD) are provided. The marker being plasma miRNA including hsa-miR-1185-2-3p, hsa-miR-22-5p, hsa-miR-134-3p, hsa-miR-1909-3p and hsa-miR-107. The use of the marker and the corresponding kits are also provided. The beneficial effects are as follows: biomarkers with high diagnostic value for MCI due to AD are disclosed, which breaks through the dilemma of no convenient peripheral plasma diagnostic markers for MCI due to AD, and is conducive to the early diagnosis and early intervention of Alzheimer's disease, commonly known as senile dementia.
A diagnostic marker for mild cognitive impairment (MCI) due to Alzheimer's disease (AD), wherein the marker is plasma miRNA comprising hsa-miR-1185-2-3p, hsa-miR-22-5p, hsa-miR-134-3p, hsa-miR-1909-3p and hsa-miR-107.
A diagnostic kit for MCI due to AD, wherein the kit comprises reagents for measuring the content of hsa-miR-1185-2-3p, hsa-miR-22-5p, hsa-miR-134-3p, hsa-miR-1909-3p and hsa-miR-107 in a plasma sample.
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