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US 2021/0340567 A1Published application
Cytokine immunotherapy
AssigneeVLP Therapeutics, LLC
InventorsWataru AKAHATA, Jonathan F. SMITH
Life of this patent
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Abstract
Provided herein is a novel immunologically-active alphavirus replicon vector which comprises a nucleic acid encoding alphavirus nonstructural proteins nsp1-4 and a cytokine protein(s)/polypeptide(s), which is useful for the treatment of a cancer and/or an inflammatory disease.
Claims20
An alphavirus replicon vector comprising, a polynucleotide which encodes alphavirus non-structural proteins nsp1, nsp2, nsp3 and nsp4, and a polypeptide comprising a cytokine.
Dependencies are inferred from the claim text.