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US 2021/0340513 A1Published application
Engineered enzyme
AssigneeInscripta, Inc.
InventorsJuhan Kim, Benjamin Mijts
Life of this patent
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Abstract
The present disclosure provides a novel catalytically inactive MAD7 nuclease (dMAD7) that retains the ability to bind DNA in a sequence-specific manner. The MAD7 nuclease from which the dMAD7 has been derived was isolated from Eubacterium rectale.
Claims4
A catalytically inactive CRISPR nuclease derived from E. rectale MAD7 (dMAD7) having an amino acid sequence SEQ ID NO:
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Dependencies are inferred from the claim text.