Loading patent…
AssigneeBgi Shenzhen
InventorsHuanhuan Liu, Na Guo, Huizhen Li, Zhougang Zhang, Hongyan Han, Miaomiao Guo, Yue Zheng, Yuliang Dong, Wenwei Zhang, Chongjun Xu
Estimating the term…
The present disclosure relates to a reverse transcriptase and an application thereof. The reverse transcriptase has mutation sites such as R450H compared with the wild-type M-MLV reverse transcriptase. The reverse transcriptase has increased polymerase activity, improved thermal stability, and reduced RNase H activity.
A reverse transcriptase, comprising amino acid mutations at positions 302 and 524 compared to the amino acid sequence of SEQ ID NO:
Dependencies are inferred from the claim text.